A peptic ulcer is a disease in which defects (ulcers) are formed in the stomach and (or) the duodenum of a person. The most common cause of peptic ulcer is a man from 20 to 50 years. The disease is characterized by chronic course and cyclicity: the disease undermines the health of its owner for years, periods of exacerbation are replaced by deceptive calm. The most often ulcer makes itself felt in the spring and autumn. Ulcer disease of the duodenum is much more common than peptic ulcer. Causes Helicobacter pylori spiral microbe plays a leading role in the development of the disease, which damages the mucous membrane of the stomach and duodenum. At the same time, this microorganism can be detected more than 80% of the inhabitants of Russia, but not all suffer from peptic ulcer disease.
– Most of peptic ulcer occur either in the duodenum, or in the stomach – Ulcer may also occur in the lower oesophagus due to reflexing of gastric content – Rarely in certain areas of the small intestine. Peptic ulcers are a break in the surface lining of the stomach or duodenum deep enough to produce a crater. What causes peptic ulcers? It is now known that over 90% of duodenal ulcers are the result of infection with helicobacter pylori (HP).
The fact is, the ulcer does not develop without a number of additional factors: • stress, anxiety, depression. In this case, there is a violation of the functions of the autonomic nervous system with a predominance of the tone of the vagus nerve.
This, in turn, causes spasm of the muscles and blood vessels of the stomach. As a result, it remains without adequate nutrition and becomes vulnerable to the action of hydrochloric acid: the walls begin to be digested with caustic gastric juice. An ulcer is formed • poor heredity; • malnutrition: use of coarse and spicy food. This increases the production of hydrochloric acid. • Alcohol abuse.
Alcohol enhances the aggressive properties of gastric juice and reduces the protective properties of the mucous membrane. Nicotine enhances the production of hydrochloric acid, prevents normal digestion of food, damages the wall of the stomach, and also disrupts the development of the protective factors of the gastric mucosa in the pancreas; • uncontrolled intake of certain drugs (reserpine, corticosteroid hormones, aspirin). What's happening?
The microbe Helicobacter pylori is transmitted from person to person with close prolonged contact, for example, with kisses, through shared dishes and towels, as well as non-compliance with hygiene rules in toilets. Once in the stomach of Helicobacter, begins to actively multiply and lead subversive activities. It produces special enzymes (urease, proteases), which damage the protective layer of the mucous (inner) shell of the stomach and duodenum, disrupts cell function, mucus production and metabolic processes and causes the formation of ulcers.